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This file is located in inst/internal/analysis1.yml.
CONTENTS
SETUP__:
description: Example PopPK analysis data set
sponsor: example-project
projectnumber: EXAMPK1011F
use_internal_db: true
glue:
bmiunits: "kg/m$^2$"
flags:
covariate: [AGE:SCR, HT, AST:ALT]
lookup_file: "look.yml"
extend_file: "analysis1-ext.yml"
C:
NUM:
ID:
SUBJ: !look
TIME: !look
label: time after first dose
unit: hour
SEQ:
label: data type
values: {observation: 0, dose: 1}
CMT:
EVID:
make_factor: true
lookup: true
AMT: !look
unit: mg
DV: !look
unit: "micrograms/L"
unit.tex: "$\\mu$g/L"
AGE: !look
range: [18,50]
WT: !look
range: [40,100]
dots: {time_varying: true}
CRCL:
label: creatinine clearance
unit: ml/min
range: [15,150]
dots: {time_varying: true}
ALB: !look
range: [1.2,6]
BMI: !look
range: [18,25]
unit.tex: <<bmiunits>>
AAG:
short: alpha-1-acid glycoprotein
unit: mg/dL
range: [50,120]
SCR:
about: [serum creatinine, mg/dL]
range: [0.7,6]
AST:
short: aspartate aminotransferase
range: [10,36]
ALT:
short: alanine aminotransferase
range: [10,35]
HT: !look
range: [140, 222]
unit: cm
CP: !look
short: Child-Pugh score
values: {normal: 0, Pugh1: 1, Pugh2: 2, Pugh3: 3}
dots: {updated_from_lookup: false} # these dots used in tests
TAFD:
short: time after first dose
unit: hours
dots: {timecol: true}
TAD:
about: [time after dose, hours]
dots: {timecol: true}
LDOS:
short: last dose amount
unit: mg
MDV:
BLQ:
short: below limit of quantification
values:
above QL: 0
below QL: 1
PHASE:
short: study phase indicator
values: 1
dots: {categorical: true}
STUDY:
short: study number
values: {SAD: 1, MAD: 2, Renal: 3, Hepatic: 4}
RF:
short: renal function stage
values: {Normal: norm, Mild: mild, Moderate: mod, Severe: sev}